Online Hormone Therapy for Men & Women: A Nurse’s Honest Review

Hormone replacement therapy used to mean waiting months for a specialist referral, sitting in a clinic, and juggling appointments. Now there’s a wave of online hormone clinics promising lab panels, tailored treatment plans, and ongoing support from home.

With a Master’s in Psychology and an MSc in Nursing underway, I’m interested in hormones from both sides: how they affect mood, motivation, and behavior, and how they show up in real bodies and real lives. In practice and training, I meet a lot of people who say some version of, “Something’s changed and I don’t feel like myself anymore.” Sleep is off. Energy is unpredictable. Body composition has shifted. Libido and mood don’t match how they “should” feel on paper.

For some, perimenopause or menopause is clearly part of the story. For others, low testosterone or broader hormone imbalance is on their mind, but they’re not sure where to start or how seriously to take what they’re noticing. That’s the gap online hormone services are trying to fill: more access, more testing, and more time spent on symptoms that are easy to brush off.

So who are the big names in online hormone care, and are they actually any good? Below, I’ll walk through the platforms you’re most likely to see, what they really offer, and how they line up with current hormone guidance. This isn’t about chasing a “new you” in a couple of weeks – hormones don’t work like that. But in the right hands, with sensible monitoring, hormone therapy can be a genuinely useful tool for the right person at the right time.

Online Hormone Services at a Glance

• Lifeforce – Best for data-driven, whole-body optimization (men & women)
  
• Winona – Best for convenient menopause HRT at home (women)
  
• Hone Health – Best for men focused on low testosterone
  
• Henry Meds – Best for bundled, budget-conscious hormone plans
  
• Marek Health – Best for lab-heavy, complex hormone cases
  

How Online Hormone Therapy Works

Most of the bigger US-based platforms follow a similar pattern:

• Online intake – detailed questionnaire covering symptoms, history, lifestyle, and goals
  
• Lab testing – at-home kit or partner-lab blood draw; usually sex hormones plus thyroid, lipids, glucose, and other basics
  
• Telehealth consult – a licensed clinician reviews your labs and history and decides whether hormone therapy is appropriate.
  
• Prescription & delivery – if indicated, HRT (for women) or TRT (for men) is prescribed and shipped as pills, patches, creams, lozenges, or injections.
  
• Follow-up – better clinics build in repeat labs, follow-up visits, and dose adjustments
  

Done well, this broadly matches current guidance: HRT is one of the most effective treatments for hot flashes, night sweats, and genitourinary symptoms of menopause, and it can support bone health. TRT is meant for men with clear symptoms and consistently low testosterone on blood tests, with regular monitoring.

Done badly, it drifts into “you’re tired, here’s some hormones,” which isn’t how endocrinology – or safe prescribing – works.

How I Chose These Hormone Services

I focused on a few non-negotiables:

• Qualified prescribers & real oversight – clinicians with hormone experience, not just a sales funnel
  
• Proper assessment – no prescribing off a two-minute quiz; labs and your past medical history matter
  
• Monitoring & follow-up – hormones affect cardiovascular risk, clotting, and mood; regular monitoring is important
  
• Transparency about risks & limits – clear about who shouldn’t use HRT/TRT; no “anti-ageing miracle” claims
  
• Real-world usability – clear pricing, the ability to pause or cancel, and support if something feels off
  

With that lens on, here’s how the main players stack up.

Lifeforce – Best for Data-Driven, Whole-Body Optimization

If you’ve ever wished someone would step back and look at all your labs together instead of one hormone number in isolation, Lifeforce is probably the closest you’ll get online.

Rather than selling “just HRT” or “just TRT,” Lifeforce runs as a longevity-style membership for men and women, with care delivered by clinicians. As a nurse-in-training and health writer, I think it’s one of the few platforms that actually feels like a joined-up approach to hormones rather than a quick-fix scheme.

How Lifeforce works (in brief)

• Broad lab panel: 50+ biomarkers – sex hormones, thyroid, lipids, inflammation, nutrients, and more
  
• At-home blood draw: In many areas, a phlebotomist comes to your home
  
• Structured consults: longer video visits to review results, symptoms, and goals
  
• Custom plan: lifestyle changes, supplements, and – where appropriate – hormone therapy
  
• Ongoing monitoring: repeat labs every few months, plus coaching and follow-up
  

Hormones aren’t treated as a stand-alone “fix”. Sleep, stress, metabolic health, training, and mood all feed into how you feel, and Lifeforce at least attempts to connect those dots instead of chasing a single “perfect” hormone value.

Lifeforce is a good fit if you:

• Want a broad, lab-based view of your health, not just a quick menopause or low-T prescription
  
• Like regular testing, clear numbers, and built-in accountability
  
• Want something that works for both men and women.
  

Watch out for:

• It’s at the premium end compared to simpler menopause-only or TRT-only clinics
  
• Branded supplements and add-ons are convenient but not cheap.
  
• Some users report slow prescription processing and admin glitches.
  

Winona – Best for Convenient Menopause HRT at Home

If your main concern is, “I’m peri/menopausal, I feel awful, and I just want sensible HRT without a fight,” Winona is one of the most visible telehealth platforms.

They focus on women’s hormone health around menopause and offer:

• An online questionnaire and clinician review
  
• Assessment by a US-licensed prescriber
  
• Estrogen, progesterone, and sometimes DHEA or testosterone
  
• Medication shipped to your door, often via compounding pharmacies
  

They target the real-life symptom list: hot flashes, night sweats, sleep problems, brain fog, mood swings, vaginal dryness, low libido, joint aches, and weight changes.

The “bioidentical” angle just needs a clear head. Winona offers both standard, FDA-approved bioidentical HRT and custom-compounded creams or combinations. “Bioidentical” itself is mostly a marketing word – plenty of regular, regulated HRT is also bioidentical. The bigger safety question is whether you’re using tightly regulated products or compounded preparations, where dose consistency can vary a bit more.

Winona might suit you if you:

• Are peri or post-menopausal and want straightforward HRT
  
• Like a service built purely around menopause care
  
• Are okay with online consults and mail-order meds
  

Things to ask:

• Do you have a strong family history of hormone-sensitive cancers or clotting disorders? If yes, I’d still want an in-person specialist in the loop.
  
• Is your prescription FDA-approved HRT, compounded HRT, or a mix – and what does that mean for monitoring and risk?
  
• How does the monthly cost compare with other telehealth or local options?
  

Hone Health – Best for Men Who Want a Focused TRT-First Approach

If you’re a man who’s tired, flat, not building muscle like you used to, and wondering if low testosterone is part of the picture, Hone Health is one of the main names you’ll see. It’s built specifically around male hormone optimization rather than general wellness.

How Hone Health works

• At-home finger-prick test: checks testosterone plus a small panel of related markers
  
• Telehealth consult: a provider reviews your results and symptoms to decide whether you genuinely meet criteria for low testosterone.
  
• Treatment: if appropriate, they can prescribe TRT (usually injections, sometimes gels/patches) or other meds like clomiphene or anastrozole
  
• Ongoing care in the app: labs, dose changes, and questions are managed via their online platform
  

Where Hone does well:

• TRT is the main event, not an add-on
  
• Low-friction entry point if you’d rather not sit in a waiting room discussing energy levels and erections
  
• More than one medication route, which helps if fertility or specific side effects are a concern
  

Hone Health is a good fit if you:

• Have classic low-T symptoms (low libido, low mood, less muscle, poor recovery)
  
• Want a men-only, TRT-focused service.
  
• Are comfortable with injections or other delivery methods, and are okay with a subscription-style cost
  

Things to think about:

• Finger-prick tests are convenient but not as robust as full venous blood draws – I prefer clearly timed morning samples and repeat tests for borderline results.
  
• Costs can add up once you combine consultations, follow-ups, and meds – TRT is a long-term commitment.
  
• TRT is not a cure-all for every tired, stressed man; sleep, mental health, and lifestyle still matter.
  
• The usual TRT risks still apply: changes in blood counts, prostate markers, cardiovascular risk – so labs and monitoring are non-negotiable.
  

Henry Meds – Best for Bundled, Budget-Conscious Hormone Plans

If cost is the main thing between you and hormone treatment, Henry Meds is a wallet-friendly option. Many people arrive here after being quoted far higher prices elsewhere, especially if they’re uninsured or under-insured.

The headline is bundled pricing: in many cases, your monthly fee covers consult, medication, and ongoing provider access instead of separate line items.

How Henry Meds works

• Online intake plus a telehealth visit with a nurse practitioner or other clinician
  
• Compounded medications (often TRT and related therapies) through partner pharmacies
  
• Bundled monthly cost that typically includes meds, supplies, shipping, and provider access
  
• Follow-up online for refills and dose adjustments
  

Where Henry Meds does well:

• Typically cheaper than many “premium” hormone clinics
  
• Predictable monthly costs can make it easier to commit and stay consistent.
  
• Fully remote, which is ideal if you’re busy or far from specialists
  

Things to be careful about:

• Customer service and billing aren’t perfect; some people report issues canceling or getting quick responses – keep an eye on your account
  
• Medication and delivery delays matter more with hormones – order refills early to avoid gaps.
  
• Most meds are compounded, which don’t go through the same FDA review process as branded drugs; that doesn’t make them “bad”, but you should be clear on what you’re taking and why
  

Marek Health – Best for Lab-Heavy, Complex Hormone & Performance Cases

If Lifeforce feels comprehensive, Marek Health is the “test almost everything and build from there” option. It’s popular with people who train hard, track everything, and feel like standard bloodwork has never really joined the dots.

How Marek Health works

• Advanced lab panels: big, multi-marker panels covering hormones, thyroid, metabolic health, inflammation, nutrients, and more
  
• Deep-dive consults: a clinician or coach walks you through results, explains the jargon, and links labs to how you actually feel and perform
  
• Personalized plan: may include TRT (for men who meet criteria), thyroid support, other meds, training and nutrition changes, and targeted supplements
  
• Follow-up: repeat labs and plan tweaks over time
  

Where Marek shines:

• They look at patterns and ratios, not just one “magic” hormone number.
  
• Coaching gets a lot of praise for clear, practical explanations.
  
• It’s a good fit if you’ve already done the basics (diet, training, basic labs) and still feel off.
  

Marek might be right for you if you:

• Have tried simpler HRT/TRT options and still don’t feel great
  
• Have multiple unexplained symptoms or odd lab results and want a full-body view
  
• Like digging into data and want a clinician to help turn that into a plan.
  

Keep in mind:

• It’s not the budget choice – all that extra testing and time costs more
  
• More data isn’t automatically more clarity; you need to lean on the clinical team, not self-treat one “suboptimal” number
  

When Online HRT / TRT Isn’t the Right Fit

As convenient as online hormone care can be, there are times when a telehealth-only route isn’t right.

You should choose in-person care if you:

• Have a personal history of hormone-sensitive cancer, clotting disorders, or uncontrolled cardiovascular disease
  
• Have unexplained vaginal bleeding, testicular changes, or other red-flag symptoms that need a physical exam
  
• Are experiencing severe mental health changes (for example, suicidal thoughts or psychosis)
  

Most reputable online providers will screen for these and either decline to treat or ask you to see a local doctor first. If a platform has no clear “we don’t treat” criteria, that’s a sign to be cautious.

Once you strip away the branding, the question is simple: what problem are you really trying to solve? As someone who cares a lot about people feeling heard, the most important thing is that you feel like a partner in the process, not just a subscriber.

Hormones can absolutely be part of putting your health back together, but they’re just one piece of the puzzle.