Best Natural Reflux Supplements Worth Trying

If you’re an acid reflux/GERD sufferer, you’ve probably already tried all of your traditional, over-the-counter options as far as antacids go. But, depending on your reflux treatment of choice, the side effects may be significant and could have long-term effects on your overall health. 

If you’re looking for a more natural alternative to supplement or replace your current reflux treatment, you’ve come to the right place.

I searched across the internet for natural reflux supplements that actually work.

Best Natural Reflux Supplements at a Glance

Actual, science-backed natural reflux supplements with tons of positive reviews.

1. Reflux Gourmet Alginate Supplements– Best overall
2. Stomach Soothe from Soothe Naturals– Best prebiotic
3. Zenwise Digestive Enzymes– Best budget option
4. Beekeeper’s Naturals Total Gut Health– Best supplement with propolis
5. DS-01® Daily Synbiotic from Seed– Best probiotic
6. Iberogast– Best tried-and-true herbal remedy

How Do Natural Supplements for Acid Reflux Work?

Traditional medicinal treatments for reflux typically either soothe the esophagus, balance or neutralize stomach acid, create a strengthened type of barrier between the stomach and esophagus to prevent acid buildup, or improve general digestion. They often do this through the use of 

Natural supplements rely on both similar and entirely innovative methods to reduce the symptoms of reflux. The most common methods that natural supplements use to reduce reflux symptoms are:

Balancing/Neutralizing Stomach Acid Naturally

Similar to traditional reflux treatments, many natural reflux supplements also work by balancing or neutralizing stomach acidity. They just do this using more natural ingredients compared to the ones more traditional remedies use.

While OTC products work on the actual acid-producing proton pumps to inhibit them from overproducing, or calcium carbonate (TUMS) or bismuth subsalicylate (Pepto-Bismol), natural reflux supplements use naturally alkaline substances like sodium bicarbonate. They could also use real-food acid-fighters like peppermint or ginger root (Zenwise Digestive Enzymes).

Creating a Physical Barrier via Alginates

This one is a little bit more advanced. Some natural reflux supplements use what’s called alginates (a carbohydrate found in brown algae) to form a gel-like substance called a raft that floats on top of your stomach acid to prevent it from spilling up into your esophagus.

It’s like creating a natural slime shield that naturally protects your esophagus from damaging and painful stomach acid.

Regulating Overall Gut Health

If you have GERD, you likely suffer from other digestive concerns. Many natural supplements work by improving overall gut health to not only treat excessive acid, but also improve digestion, reduce bloating and gas, and regulate bowel movements.

Natural supplements do this by using probiotics and prebiotics that balance the digestive system by using live cultures. These work to help your digestive system do what it already does, but better, which helps reduce the symptoms of GERD.

A few of the natural supplements on this list that regulate overall gut health are Beekeeper’s Naturals Total Gut Health and DS-01 Daily Synbiotic.

Reducing Inflammation

Last but not least, many supplements actually work by reducing inflammation, which is both a cause and a symptom of GERD. Esophagitis and gastritis, which cause symptoms similar to those of GERD, are inflammatory issues that these supplements work well in treating. GERD, on the other hand, can lead to irritation and inflammation of the esophagus, which worsens heartburn.

Anti-inflammatory natural reflux supplements use ingredients like slippery elm and marshmallow root to coat the esophagus with a lining that allows the tissue to heal while reducing irritation, and herbs like chamomile and lemon balm to calm spasms and soothe inflamed organs.

Iberogas (a long-trusted natural reflux supplement made up of different herbs) and Soothe Naturals (which uses slippery elm and marshmallow root to coat the esophagus) are two examples of anti-inflammatory natural supplements for reflux.

Benefits of Natural Reflux Supplements

Natural reflux supplements offer a ton of benefits to users who suffer from GERD and other reflux issues, including:

• Address root causes, not just symptoms- Natural reflux supplements usually contain a mix of gut-friendly ingredients to actually address issues like mobility and gut balance over time, rather than offer temporary relief from symptoms.
• Improve overall digestive health- Natural reflux supplements go beyond acid neutralization to improve your gut biome, help your digestive system do its job more effectively, and allow you to absorb nutrients better from the foods you’re eating.
• Help heal the esophagus and stomach lining- Many of the ingredients in natural supplements for reflux create a barrier that soothes irritation while letting the tissue actually heal, rather than just masking the burning sensation.
• Create barriers instead of reducing acid- Acid reduction can make it harder to digest food. Many natural supplements create physical barriers to keep stomach acid where it should be, without creating a rebound effect.
• Fewer long-term side effects- Your usual reflux meds (especially PPIs) can cause some long-term side effects, like microbiome disruptions, decreased nutrient absorption, and rebound acid.

How I Picked These Natural Reflux Supplements

Since treatment differs so much from person to person and everybody has different needs when it comes to reflux management, I wanted to make sure I had a large variety of actually effective natural reflux supplements. Whatever your needs and concerns are, there’s something on this list for you.

Here’s what I looked at when comparing these natural reflux supplements:

• How they work- Natural supplements have different approaches in how they treat and manage reflux symptoms, so I wanted to have options on this list that worked by neutralizing or balancing stomach acid naturally, forming a protective barrier to stop acid from rising, reducing inflammation in the digestive tract, and supporting gut health and better motility.
• Actual evidence- Since there is a ton of (often valid) skepticism when it comes to natural remedies, I wanted to highlight products that held actual clinical studies or included ingredients that are scientifically proven to reduce reflux symptoms and soothe the digestive system.
• Quality and ingredient transparency- Since supplements are not subject to the same regulation as traditional medicines, I wanted to make sure the supplements on this list are transparent about their ingredients, use high-quality sourcing, and undergo third-party testing.
• Safety- Acid reflux is a chronic condition, so you’ll probably use these products for an extended period of time, if not for your whole life. I chose products that are safe for regular use over time.
• Reviews and results- All of the products on this list have hundreds to thousands of positive reviews from real-world people who were satisfied with their results.

The Best Natural Supplements for Reflux

1. Reflux Gourmet Alginate Supplements

Best overall

Topping the list is the alginate reflux treatment line from Reflux Gourmet, a company that offers a few different products to naturally treat reflux using a polymer found in sea kelp.

Alginate works to create a gel-like raft barrier on top of the stomach at the bottom of the esophagus to stop reflux altogether. Alginate therapy has no known side effects and has been used safely in food for over a century, making it an appealing alternative to traditional medicines for reflux.

This type of natural supplement comes in a gel form, which does a great job of soothing and coating the throat, but usually tastes, well, like seaweed. Not appetizing for many. Reflux Gourmet does a great job of eliminating that bitter grassy taste by infusing tasty natural flavors that make taking your reflux treatment easy.

They offer a few different products, including the original Reflux Gourmet Rescue, which comes in a flavored gel available in vanilla caramel and mint chocolate, and Reflux Gourmet Raft, available in lemon ginger and midnight berry. There’s also a gum (available in berry or tropical flavor), which offers the added benefit of gum (swallowing more frequently soothes acid reflux faster).

From personal experience, I enjoy the flavors of these supplements, and the added soothing benefits are another huge selling point for me. The only bummers are the frequency of how often you take it (1 teaspoon after every meal and before bed) and the price (around $30 per product, definitely not the priciest on this list). Still, I can see this being a great option for people who want a side-effect-free option or who struggle with swallowing pills.

2. Stomach Soothe from Soothe Naturals

Best prebiotic

For a prebiotic that treats reflux and other gut health issues holistically, check out Stomach Soothe from Soothe Naturals. 

It uses proven stomach-soothing ingredients like slippery elm and arrowroot that protect the stomach lining, plus whole foods like green banana, papaya, and apple for natural enzymes, prebiotics, and digestive support. L-glutamine strengthens your stomach and esophagus lining while reducing inflammation, making it a versatile daily supplement for both immediate relief and long-term, continuous gut healing. 

Unlike other remedies that use acidic ingredients, Stomach Soothe uses gentle herbs and fruits to calm reflux. Plus, it’s free of additives, fillers, and “natural flavors” for a clean, daily gut health solution. 

Unfortunately, it’s on the pricier end ($38 for a pouch of 30 servings), and since it’s an unflavored powder that you add to water, it’s not the most pleasant to consume.

3. Zenwise Digestive Enzymes

Best budget option

If you’re on a budget, this is going to be your best bet. 

Zenwise Digestive Enzymes is a great, budget-friendly ($20 for 60 capsules!) option that contains a potent blend of enzymes, probiotics, and prebiotics to not only balance acid reflux but also support smoother digestion and reduce gas, bloating, and discomfort. 

It also contains other useful botanicals like ginger, turmeric, fennel, and peppermint for natural gut healing, plus the spore-forming probiotic DE111® that offers reliable gut support. This one has a high-quality plant-based formula designed to help with everything from hard-to-digest meals to everyday digestive issues. 

Zenwise has a ton of positive reviews across multiple sites from long-time, loyal customers with issues ranging from GERD to IBS who love what it’s done for their digestive system. The big downside of these is that the capsules are pretty large, making taking your meds tricky for some.

4. Beekeeper’s Naturals Total Gut Health

Best supplement with propolis

Beekeeper’s Naturals Total Gut Health is a propolis-rich formula that soothes the digestive tract and supports your gut lining. 

Propolis is a pollen-derived prebiotic that contains antioxidants and anti-inflammatory compounds to help protect the esophagus and stomach, reduce oxidative stress, and strengthen the intestinal barrier, lowering usual reflux triggers. Combined with spore-based probiotics and postbiotics like tributyrin, it promotes a balanced microbiome, reduces bloating, and supports healthier digestion. 

Users report less heartburn, gas, and general stomach discomfort after just 28 days of use. One downside is that some users may find the taste or texture of propolis-based supplements off-putting, and results can take a few weeks to appear, making it not a great option for providing immediate relief. Plus, it’s $45. Yikes.

5. DS-01® Daily Synbiotic from Seed

Best probiotic

The “take a probiotic” team is actually onto something here; probiotics are a great treatment for reflux, and you aren’t going to find a better one than DS-01® Daily Synbiotic from Seed.

This probiotic offers a clinically proven blend of 24 strains plus a patented prebiotic to support digestion, reduce bloating, and strengthen the gut barrier. Backed by multiple gold-standard, double-blind, placebo-controlled trials, DS-01® has been proven to improve bowel regularity, ease digestive discomfort, and provide relief from symptoms like burning and bloating that can trigger acid reflux. 

This high-quality formula also supports immune, skin, and heart health by promoting a balanced microbiome and strengthening your gut lining. 

While it really does offer amazing results, the huge downside is that it’s the priciest option on this list at $50 for a 30-day supply. If you’re serious about gut health and have the dough to spend, it’s worth it.

6. Iberogast

Best tried-and-true herbal remedy

You’ll find good old Iberogast on just about every natural reflux supplement list out there, and for good reason. This tried-and-true, all-natural herbal supplement has long been a go-to natural digestive solution for everything from reflux to nausea, gas, and diarrhea.

Iberogast uses a clinically proven, proprietary 6-herb blend that has been studied for over 60 years. It works by calming and soothing the digestive tract while helping restore normal digestive function, relieving symptoms like heartburn, bloating, indigestion, nausea, and gas. 

Backed by four clinical studies, Iberogast combines high-quality herbs with equally high production standards that produce consistent, reliable results. The dual-action formula makes it a great option for natural, plant-based digestive relief and regulation.

Which Is the Best Natural Supplement for Reflux?

The best natural reflux supplement is going to depend on your personal needs and preferences. The best overall, offering fast-acting relief that’s safe enough to take daily, Reflux Gourmet’s products are right in that sweet spot of effectiveness and price. For a low-cost option, try Iberogast for Zenwise Digestive Enzymes. And for a luxury probiotic that offers overall health improvement, Seed’s DS-01® Daily Synbiotic is hard to beat.